M.S. in Clinical & Translational Science
The deadline for applications is May 31 for a start date of August 20, 2012.
Objective: Develop the next generation of clinical and translational scientists through educational and mentored, research training
Target Group: Initial enrollment is limited to faculty, clinicians, and health professional students residing at the health sciences centers of West Virginia University (campuses at Morgantown, Eastern Division, Charleston Division/Charleston Area Medical Center, and the West Virginia School of Osteopathic Medicine.
M.S. Degree (34 credits)
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Didactic coursework – 25 credits;
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Required Courses (19 credits)
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Elective Courses (6 credits)
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Thesis Research - 9 credits
The M.S. degree expands upon Certificate coursework and culminates with a written thesis or first-author publication. The peer-reviewed first-author publication or written thesis is defended orally to a four-member committee comprised of the trainees WVCTSI faculty research co-mentors, one additional WVCTSI faculty, who must be outside of the Scholar’s department, and one funded faculty member from another institution. Elective courses allow trainees to tailor their education to match their research or interests. See Table 2 and 3 for courses.
The M.S. research project must make an original contribution to translating scientific knowledge from the bench to bedside (T1), to larger patient populations (T2), to the practice area for dissemination and implementation (T3), and/or to new policy or outcomes research (T4). The M.S. degree requires a peer-reviewed first-author publication or written thesis that is defended orally to a four-member committee comprised of the trainees WVCTSI faculty research co-mentors, one additional WVCTSI faculty, who must be outside of the Scholar’s department, and one funded faculty member from another institution.
Application Process: Interested applicants apply electronically at www.http://majors.wvu.edu/home/details/229. The deadline for application is May 31 for a start date of August 20, 2012. The application requires a personal statement outlining past accomplishments with an emphasis on research, your future research interests, and a clear career vision of becoming a clinical/translational researcher, three letters of recommendation that evaluate your potential as a clinician scientist, a list of potential research mentors, and an NIH Biographical Sketch. For faculty applicants, a support letter from the Department Chair is required stating how research activities integrate with clinical (if appropriate), teaching, and/or service responsibilities. For clinicians support letters from the Department Chair and fellowship/residency director (if applicable) are required stating how research activities integrate with clinical (if appropriate), teaching, and/or service responsibilities. Student applicants must be in good academic and professional standing. The WVCTSI Educational Committee will review all applications, interview selected applicants, and notify applicants of admission decisions by late July.
A limited number of tuition scholarships are available.
Transfer Credits: Trainee participants with prior graduate coursework in population health and health outcomes are allowed to transfer up to 12 semester credits with grades of B or better from another accredited institution. Transfer courses substitute for required courses upon approval of the Course Coordinators and Program Assistant Director.
Table 1. M.S. Degree Coursework (34 credits) – didactic coursework (25 credits); thesis research (9 credits)
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Fall |
|
|
|
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Introduction to Clinical & Translational Research |
DCTS |
1 |
Faculty |
|
Applied Biostatistics (web/live) Or Intermediate Biostatistics |
BIOS 601, BIOS 610 |
3 |
G. Kelley
C. Ice |
|
Applied Biostatistics Lab |
BIOS 602 |
1 |
G. Kelley |
|
Public Health Epidemiology (Web/live) Or
Principles of Epidemiology I
|
EPID 601,
EPID 610
|
3 |
I. Rockett
A. Shankar
|
|
Research Translation for Health |
SBHS 711 |
3 |
G. Dino |
|
Ethics (RCR), Discussions on Scientific Integrity |
BMS 700 |
1 |
Faculty |
|
Health Disparities Journal Club |
DCTS |
1, Every other week for 2 h |
Faculty |
|
Research & Work in Progress Meetings |
BMS 797 |
1 |
Co-Mentors |
|
WVCTSI Symposium |
|
Monthly |
Faculty |
|
Learning/Mentoring Community |
|
Monthly |
Role Models |
|
Spring |
|
|
|
|
Principles of Clinical Trials |
EPID |
3 |
K. Innes |
|
IRB Committee, Protocol Review &
Scientific Protocol Review Monitoring Committee
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|
Attend each on a monthly basis, Includes session on Clinical Trials Ethics & Conduct |
S. Davis, chair
W. Petros, chair
|
|
Elective – T1/2 or T3/4 |
|
3 |
|
|
Elective – T1/2 or T3/4 |
|
3 |
|
|
Health Disparities Journal Club |
DCTS |
1, Every other week for 2 h |
Faculty |
|
Research & Work in Progress meetings |
BMS 797 |
3 |
Co-Mentors |
|
WVCTSI Symposium |
|
Monthly |
Faculty |
|
Learning/Mentoring Community |
|
Monthly |
Role Models |
|
Summer |
|
|
|
|
Scientific Writing & Grantsmanship |
BMS 720 |
2 |
B. Schreurs |
|
Research & Work in Progress meetings |
BMS 797 |
5 |
Co-Mentors |
|
WVCTSI Symposium |
|
Monthly |
Faculty |
Table 2. Electives Courses (T1&T2 and T3&T4).
T1&T2 Electives
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Survey Research Methods |
SBHS 660, 3 credits |
|
X |
|
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Molecular Diagnosis in Public Health |
OEHS 770, 3 credits |
X |
|
|
|
Principles of Clinical Pharmacology |
CCMD 793b, 2 credits |
|
|
X |
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Epigenetics and Systems Biology |
PUBH 791, 3 credits |
|
X |
X |
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Qualitative Research Methods |
SBHS 712, 3 credits |
|
X |
|
|
Principles of Measurement |
NSG 730, 3 credits |
X |
|
|
T3&T4 Electives
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Intervention Design |
SBHS 612, 3 credits |
X |
|
|
|
Community-based Participatory Research Methods |
SBHS 614 |
|
|
|
|
Culture and Health |
NSG 593, 3 credits |
X |
|
|
|
Health Services/Outcomes Research Methods |
PUBH 618, 3 credits |
|
|
|
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Introduction of Outcomes Research: Patient Reported Outcomes |
PUBA 670, 2 credits |
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X |
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Policy and Leadership Electives
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Foundational Health and Policy |
HPML 601, 3 credits |
X |
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|
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Public Health Leadership and Management |
HPML L20, 3 credits |
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X |
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Table 3: Representative List of Clinical and Federally Funded Mentors, with identified research areas. Mentors are categorized by research area and type of translational research T1 to T4 (T1, bench to bedside; T2, to larger patient populations; T3, to the practice area for dissemination and implementation; and T4, to new policy or outcomes research
Remick, Scot, MD
Abraham, Jame, MD
Craig, Michael, MD
Agazie, Yehenew, PhD
Frisch, Steven, PhD
Gibson, Laura, PhD
Guo, Lan, PhD
Majeswski, Stan, PhD
Pugacheva, Elena, PhD
Raylman, Ray, PhD
Rojanasakul, Yon, PhD
Ruppert, J. Michael, MD, PhD |
Cancer
T3-T1: Cancer therapeutics and AIDS malignancies
T2-T1: Breast cancer and cancer chemotherapy
T2-T1: Novel chemotherapies
T1: Tyrosine phosphoryl. (SHP2) and breast cancer
T1: Anoikis and epithelial-mesenchymal transition
T1: Tumor cells and the bone marrow microenvironment
T1: Novel biomarkers
T1: Novel PET/CT imaging
T1: Adhesions proteins in activation of mitotic signaling
T1: Novel PET imaging
T1: Lung carcinogenesis and fibrosis
T1: Epithelial cancers; signaling by KLF4 & Gli1
|
Neal, William, MD
Finkel, Mitch, MD
Gurka, Matthew, PhD
Mustafa, Jamal, PhD
Piedimonte, Giovanni, MD
Dey, Richard, PhD
Nurkiewicz, Timothy, PhD |
Cardiopulmonary
T4-T1: CARDIAC; childhood cardiovascular disease
T2-T1: Pharmacotherapies for cardiac patients
T2-T1: Biostatistician; metabolic syndrome in children
T2-T1: Coronary flow regulation and adenosine; asthma
T2-T1: Environmental factors in childhood lung disease
T1: Airway reactivity and ozone exposure; asthma
T1: Effects of nanoparticle exposure on microvasculature
|
Madhavan, Suresh, PhD
Narsavage, Georgia, PhD, RN
Sambamoorthi, Usha PhD
Frisbee, Stephanie, PhD
Shelton, Deborah PhD, RN
Hendryx, Michael, PhD |
Health Services, Outcomes, and Policy
T4-T3: Health services research and health policy
T4-T3: Health Outcomes; post hospital monitoring
T4-T3: Health economics, global and women’s health
T4-T2: Policy & epidemiology: cardiovascular health outcomes
T4-T1: Health services research – correctional health
T3-T1: Health disparities of Appalachian coal communities |
Cottrell, Leslie, PhD
Dino, Geri, PhD
Horn, Kim, PhD
Kelley, George, PhD
Hillgartner, F. Brad, PhD
Hollander, John, PhD
Matsumoto, Rae, PhD
O’Donnell, James, PhD
Salati, Lisa, PhD |
Human Behavior, Obesity, and Substance Abuse
T4-T1: National’s Children Study; childhood obesity
T4-T1: Director, WV Prevention Research Center; tobacco
T4-T1: Director, Translational Tobacco Research Program
T2-T1: Meta analysis of exercise, diet, and nutrition
T1: Nutritional regulation of genes in metabolic disease
T1: Cardiac contractile abnormalities; diabetes
T1: Novel pharmacology for drugs of abuse
T1: Depression, anxiety; neuropharmacology
T1: Nutritional control of metabolism; gene expression
|
Coben, Jeffrey, MD
Crout, Richard, DMD, PhD
Shankar, Anoop, MD, PhD
He, Pingnian, MD, PhD
Klinke, David, PhD
Pei, Ming, MD, PhD
Sundaram, Uma, MD |
Inflammationand Injury
T4-T2: Injury control and prevention
T3-T1: Oral inflammation; oral health disparities
T2-T1: Biomarkers and epidemiology of inflammation
T1: Inflammation and microvascular permeability
T1: Computational & engineering analyses of biol. subjects
T1: Adult stem cell proliferation and differentiation
T1: Inflammatory bowel disease; ion transport
|
Rosen, Charles, MD, PhD
Agmon, Ariel, PhD
Berrebi, Albert, PhD
Goodman, Robert, PhD
Huber, Jason, PhD
Ramamurthy, Vishy, PhD
Schreurs, Bernard, PhD
Sokolov, Maxim, PhD
Spirou, George, PhD |
Substance Abuse – Tobacco and other Drugs
T2-T1: Stroke; blood brain barrier; brain tumors & injuries
T1: Synaptic circuitry and development in hippocampus
T1: Neuronal microcircuits in central auditory pathways
T1: Neuronal mechanisms controlling GnRH from hypothal.
T1: Blood brain barrier and stroke
T1: Neuronal death, glaucoma, and blindness
T1: Learning & memory, synaptic plasticity, Alzheimer’s
T1: Retinal defects; chaperones &neurodegeneration
T1: Sensory neuroscience deficits
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